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Zh Nevrol Psikhiatr Im S S Korsakova ; 123(3): 130-136, 2023.
Article in Russian | MEDLINE | ID: covidwho-2276728

ABSTRACT

OBJECTIVE: To study the effect of phenosanoic acid therapy on the frequency of seizures, asthenia and quality of life of adult patients with focal epilepsy who had a new coronavirus infection caused by SARS-CoV-2. MATERIAL AND METHODS: The data of 20 patients with focal epilepsy who suffered COVID-19 and received therapy with phenosanic acid (Dibufelon) were studied. The frequency of epileptic seizures, the severity of asthenia and the quality of life were evaluated according to clinical scales. RESULTS: Significant decrease in the frequency of bilateral tonic-clonic seizures and focal seizures with loss of consciousness was recorded. There was a significant improvement in the quality of life. There was no significant dynamics of asthenia against the background of taking the drug phenosanic acid in patients. CONCLUSION: The preparation of phenosanic acid can be an effective means of add-on therapy in patients with epilepsy who have undergone COVID-19.


Subject(s)
COVID-19 , Epilepsies, Partial , Epilepsy, Tonic-Clonic , Epilepsy , Adult , Humans , Anticonvulsants/therapeutic use , Asthenia/drug therapy , Quality of Life , SARS-CoV-2 , Seizures/drug therapy , Epilepsies, Partial/drug therapy , Epilepsy/drug therapy
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